女主人公的家庭生活很不幸福,婚姻走到了崩溃的边缘,然而这时一场突发的意外使她丧失了之前15年的记忆。不再为过去的糟糕经历所累的她,婚姻又开始出现了转机。。Alice and Niklas are happy, they lack nothing - but a child. After several failed invitros, they go on a holiday to Sardinia to leave their wish for a child behind. Right there, however, everything they tried to repress resurfaces. A cheerful Tyrolean family moves directly into the neighboring house and seems to have everything that Alice and Niklas lack in life. An unforeseen ...。一场可怕的车祸让克莱尔(詹妮弗·安妮斯顿 Jennifer Aniston 饰)不仅容貌尽毁,还失去了挚爱的儿子,之后,深陷于绝望和痛苦中无法自拔的克莱尔患上了慢性疼痛症。为了同疾病做斗争,克莱尔来到了慢性疼痛俱乐部,通过和病友们的相互交流与鼓励,获得生活下去的信心和希望。 妮娜(安娜·肯德里克 Anna Kendrick 饰)是俱乐部中的一员,某日,她自杀身亡的消息震惊了克莱尔。克莱尔想方设法寻求妮娜自杀的真相,最后甚至陷入了同妮娜对话的幻觉之中无法自拔,与此同时,妮娜的丈夫罗伊(萨姆·沃辛顿 Sam Worthington 饰)亦出现在了克莱尔的身旁,将克莱尔卷入了一个又一个漩涡之中。。